10 moxidectin in glyceryl tristearate microspheres was evaluated in four studies using beagle dogs and one study using ivermectin sensitive collies.
Moxidectin injection for dogs.
Moxidectin is a drug that is used to treat parasites in dogs cats and large farm animals.
In a laboratory effectiveness study dogs with 4 and 6 month old heartworm infections administered moxidectin microspheres at a dose of 0 17 mg kg experienced vomiting lethargy and bloody diarrhea.
The safety of proheart 12 ph 12.
Moxidectin is also available in combination products as with advantage multi.
Cydectin injectable is specially formulated to allow moxidectin to be absorbed from the site of injection and distributed internally to the areas of the body affected by endo and or ectoparasitism.
His love is unconditional and so is yours.
In a laboratory study 16 beagle dogs implanted with adult heartworms d.
It works similarly to other anthelmintic drugs like ivermectin and milbemycin by interfering with important neurotransmissions in parasites so that they become paralyzed and die.
Dosing information of moxidectin for dogs.
Moxidectin is available in 30 mcg 68 mcg and 136 mcg tablets.
The recommended dose is 0 5 mg kg subcutaneously once yearly.
It has recently been made available as a 10 percent moxidectin injection in 20 ml vials.
When it comes to protecting your best friend against heartworm disease proheart 6 moxidectin makes it simple.
This is a topical solution product to be applied on the skin every month.
Food and drug administration s center for veterinary medicine announced today the approval of proheart 12 moxidectin extended release injectable suspension for dogs 12.
Just 1 shot of proheart 6 from your veterinarian provides your dog with 6 months of protection and gives you 6 months peace of mind.
He s your best friend.
Immitis received either proheart 12 at 1 5 mg kg body weight 3x 8 dogs or a saline injection control 8 dogs.
The injection site that resolved spontaneously within 24 hours of administration.
And in case you missed it there s 3 times as much moxidectin in proheart 12 as proheart 6 so side effects are likely to be greater this is the exact list of adverse events on the label.
The product label for proheart 12 cites an alarmingly long list of adverse events of proheart 6.
The proheart 12 injection works similarly to proheart 6 but instead of providing heartworm protection for six months it will last a whole year.
It works by slowly releasing microspheres of the antiparasitic drug moxidectin over the course of 12 months.
Moxidectin is an endectocide in the milbemycin chemical class which shares the distinctive mode of action characteristic of macrocyclic lactones.